What's New

The MAL has launched a study entitled “EMG modules as a novel biomarker of basal ganglia plasticity in Parkinson’s disease”. The study funded by the Michael J. Fox Foundation aims to identify specific characteristics of muscle activity that could be linked to changes within the brain that are associated with Parkinson’s disease.

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300 First Avenue 3rd Floor, Room 3297
Charlestown, MA 02129

For Clinical Appointments & Referrals:
Susan Regan
(617) 952-6204

For Research Study Information:
Call our Volunteer Registry Line at
(617) 952-6331


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It has been estimated about 1.6 million people in the United States live with a limb loss as of 2005, with the numbers estimated to increase to 3.6 million by the year 2050. With limb loss, many patients experience changes in gait between the right and left limbs.  These changes have been characterized by unequal loading or stance times, known as, asymmetry of gait.  The changes in gait associated with a limb loss can cause many physical detriments including, lower back pain, joint overuse, pain, osteoarthritis, osteoporosis changes, and muscle imbalances, which creates serious long-term medical issues and greatly reduces that quality of life. It has been found that instrumented treadmills along with virtual-reality feedback with a therapist have helped amputees improve gait. However, due to limitations of many of the available devices to in-clinic use only, amputees have not been able to fully benefit from this technology.

Dr. Bamberg from Veristride in Salt Lake City, UT, has developed Veristride’s RapidRehab system, which targets persons with lower limb amputations, with a goal of improving their mobility and quality of life, through real-time feedback that is available anytime and anywhere. This innovation has the potential for lower cost rehabilitation which can be used away from the clinic.

The Motion Analysis Lab will be running this study. The study will consist of 3 assessments at the Motion Analysis Lab, along with 8 session of gait training with a research therapist, in a hospital every two weeks.  All individuals must undergo an initial phone screen, must meet all inclusion criteria and must undergo a final in-person screen to determine eligibility.

Inclusion Criteria:

  • · Unilateral lower-limb amputation
  • · Date of amputation or related surgery within 36 months
  • · Between the ages of 18-64
  • · Visual appreciation of gait asymmetry by the therapist (or stance time ratio <0.90, stance force ratio <0.90 and trunk sway >50 mm if measured in the Motion Analysis Lab)
  • · Cleared by a physician or physical therapist to participate

Exclusion Criteria:

  • · Subjects with severe residual limb pain that limits function
  • · Subjects at high risk of falls as determined by the therapist judgment and participant interview (review of fall history-subjects with falls within the last month will be excluded)
  • · Lower extremity impairments that interfere with its normal function and range of motion such as a orthopedic conditions, open wounds, severe swelling. Enrollment in physical therapy for improvement of gait.
  • · Any diagnosed medical condition that would interfere with subject participation in regular sustained exercise such as a severe pulmonary and/or cardiovascular condition.

If you are interested in this study and would like to participate or learn more, please contact the Motion Analysis Volunteer line at 617-952-6331. Please do not hesitate to call with any questions or concerns, which you may have.