What's New

The MAL has launched a study entitled “EMG modules as a novel biomarker of basal ganglia plasticity in Parkinson’s disease”. The study funded by the Michael J. Fox Foundation aims to identify specific characteristics of muscle activity that could be linked to changes within the brain that are associated with Parkinson’s disease.

Contact Us

300 First Avenue 3rd Floor, Room 3297
Charlestown, MA 02129

For Clinical Appointments & Referrals:
Susan Regan
(617) 952-6204

For Research Study Information:
Call our Volunteer Registry Line at
(617) 952-6331


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Scientific Journals

Our lab is continually publishing. Read more about our work in the following peer-reviewed journals.

  1. Cajigas I, Koenig A, Severini G, Smith M, Bonato P, “Robot-Induced Perturbations of Human Walking Reveal a Selective Process of Generation of Motor Adaptation”, Science Robotics, 2017: 2(6): eaamm7749 (SUMMARY)(ABSTRACT)(FULL TEXT)
  2. Ebenbichler GR, Unterlerchner L, Habenicht R, Bonato P, Kollmitzer J, Mair P, Riegler S, Kienbacher T, “Estimating Neural Control from Concentric vs Eccentric Surface Electromyographic Representations during Fatiguing, Cycli Submaximal Back Extension Exercises”, Frontiers in Physiology, 2017: 8 (OPEN ACCESS)
  3. Carvalho G, Bonato P, Florencio L, Dach F, Biqal M, Bevilaqua-Grossi D, “Balance Impairments in Different Subgroups of Patients with Migraine”, Headache, 2017; 57(3): 363-374 (JOURNAL WEBSITE)
  4. Liu L, Bonato P, Clancy T, “Comparison of Methods for Estimating Motor Unit Firing Rate Time Series from Firing Times”, Journal of Electromyography and Kinesiology, 2016; 31: 22-31 (JOURNAL WEBSITE)
  5. Espay AJ, Bonato P, Nahab F, Maetzler W, Dean JM, Klucken J, Eskofier BM, Merola A, Horak F, Lang AE, Reilmann R, Giuffrida J, Nieuwboer A, Horne M, Little MA, Litvan I, Simuni T, Dorsey ER, Burack MA, Kubota K, Kamondi A, Godinho C, Daneault JF, Mitsi G, Krinke L, Hausdorff JM, Bloem BR, Papapetropoulos S, on behalf of the MDS Taskforce on Technology, “Technology in Parkinson Disease: Challenges and Opportunities”, Movement Disorders, 2016: 31(9): 1272-1282 (JOURNAL WEBSITE)
  6. Tran D, Pajaro-Blazquez M, Daneault JF, Gallegos JG, Pons J, Fregni F, Bonato P, Zafonte R, “Combining Dopaminergic Facilitation with Robot-Assisted Upper-Limb Therapy in Stroke Survivors, A Position Paper”, Am J Phys Med Rehabil, 2016; 95(6): 459-474 (OPEN ACCESS)
  7. Schneider JC, Ozsecen MY, Muraoka NK, Mancinelli C, Della Croce U, Ryan CM, Bonato P, Feasibility of an Exoskeleton-Based Interactive Video Game System for Upper Extremity Burn Contractures, PM&R, 2016; 8(5): 445-452 (JOURNAL WEBSITE)
  8. Straudi S, Chew E, Iahn C, Fregni F, Bonato P, “Combining Transcranial Direct Current Stimulation and Gravity-Supported, Computer-Enhanced Arm Training in a Chronic Pediatric Stroke Survivor: A Case Report”, Clinical Case Reports and Reviews, 2015 21(1): 301-306 (OPEN ACCESS)
  9. Jacobson E., Meleger A., Bonato P., Wayne P., Langevin H., Kaptchuk T.J., Davis R.B., “Structural Integration as an Adjunct to Outpatient Rehabilitation for Chronic Non-Specific Low Back Pain: a Randomized Pilot Clinical Trial”, Evidence-Based Complementary and Alternative Medicine, 2015, ID 813418, 19 (OPEN ACCESS)
  10. Dai C., Li Y., Christie A., Bonato P., McGill K.C., Clancy E.A., “Cross-Comparison of Three Electromyogram Decomposition Algorithms Assessed with Experimental and Simulated Data”, IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2015 Jan;23(1):32-40 (JOURNAL WEBSITE)
  11. Coscia M., Cheung V.C.K., Tropea P., Koenig A., Monaco V., Bennis C., Micera S., Bonato P., “The Effect of Arm Weight Support on Upper Limb Muscle Synergies during Reaching Movements”, J Neuroeng Rehabil, 2014 Mar 4;11(1):22 (OPEN ACCESS)
  12. Della Croce U., Crapanzano F., Li L., Kasi P.K., Patritti B.L., Mancinelli C., Hunter D.J., Stamenović D., Harvey W.F., Bonato P., “Effects of a Novel Pneumatic Unloading Knee Brace on the Gait Mechanics of Patients with Knee Osteoarthritis”, PM&R 2013; 5(10): 816-824 (JOURNAL WEBSITE)
  13. Pietrusinski M, Cajigas I, Bonato P. Mavroidis C., Robotic Gait Rehabilitation Trainer, IEEE/ASME Transactions on Mechatronics 2013; 99: 1-10 (JOURNAL WEBSITE)
  14. Dalton A, Patel S, Chowdhury AR, Welsh M, Pang T, Schachter S, ÓLaighin G, Bonato P. Development of a Body Sensor Network to Detect Motor Patterns of Epileptic Seizures. IEEE Trans Biomed Eng, 2012; 59(11): 3204-3211 (JOURNAL WEBSITE)
  15. Cheung VCK, Turolla A, Agostini M, Silvoni S, Bennis C, Kasi P, Paganoni S, Bonato P, Bizzi E. Muscle Synergy Patterns as Physiological Markers of Motor Cortical Damage, Proceedings of the National Academy of Science. 2012; 109(36): 14652-14656 (OPEN ACCESS)
  16. Reinkensmeyer D.J., Bonato P., Boninger M.L., Chan L., Cowan R.E., Fregly B.J., Rodgers MM, “Major Trends in Mobility Technology Research and Development: Overview the Results of the NSF-WTEC European Study”, J Neuroeng Rehabil, 2012; 9: 22 (OPEN ACCESS)
  17. Patel S., Park H., Bonato P., Chan L., Rodgers M., “A Review of Wearable Sensors and Systems with Application in Rehabilitation”, J Neuroeng Rehabil, 2012; 9: 21 (OPEN ACCESS)
  18. Wayne P.M., Kiel D.P., Buring J.E., Connors E.M., Bonato P., Yeh G.Y., Cohen C.J., Mancinelli C., Davis R.B., “Impact of Tai Chi Exercise on Multiple Fracture-Related Risk Factors in Post-Menopausal Osteopenic Women: A Pilot Pragmatic, Randomized Trial”, BMC Complement Altern Med. 2012 Jan 30;12(1):7 (OPEN ACCESS)
  19. Benedetti M.G., Agostini V., Knaflitz M., Bonato P., “Muscle Activation Patterns During Level Walking and Stair Ambulation”, in Applications of EMG in Clinical and Sports Medicine, C. Steele (editor), 2012 (OPEN ACCESS)
  20. Mavroidis C, Ranky RG, Sivak ML, Patritti BL, DiPisa J, Caddle A, Gilhooly K, Govoni L, Sivak S, Lancia M, Drillio R, Bonato P., “Patient Specific Ankle-Foot Orthoses Using Rapid Prototyping”, J Neuroeng Rehabil, 2011; 8: 1 (OPEN ACCESS)
  21. Chen B.R., Patel S., Buckley T., Rednic R., McClure D.J., Shih L., Tarsy D., Welsh M., Bonato P., “A Web-Based System for Home Monitoring of Patients with Parkinson’s Disease Using Wearable Sensors”. IEEE Trans Biomed Eng 2011; 58(3): 831-836 (JOURNAL WEBSITE)
  22. Burke DT, Protopapas M, Bonato P, Burke JT, Landrum RF, “Martial Arts: Time Needed for Training”, Asian J Sports Med. 2011 Mar; 2(1): 31-36 (OPEN ACCESS)