What's New

The MAL has launched a study entitled “EMG modules as a novel biomarker of basal ganglia plasticity in Parkinson’s disease”. The study funded by the Michael J. Fox Foundation aims to identify specific characteristics of muscle activity that could be linked to changes within the brain that are associated with Parkinson’s disease.

Contact Us

300 First Avenue 3rd Floor, Room 3297
Charlestown, MA 02129

For Clinical Appointments & Referrals:
Susan Regan
(617) 952-6204

For Research Study Information:
Call our Volunteer Registry Line at
(617) 952-6331


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Scientific Journals

Our lab is continually publishing. Read more about our work in the following peer-reviewed journals.

  1. Liu L, Bonato P, Clancy T, “Comparison of Methods for Estimating Motor Unit Firing Rate Time Series from Firing Times”, Journal of Electromyography and Kinesiology, 2016; 31: 22-31
  2. Espay AJ, Bonato P, Nahab F, Maetzler W, Dean JM, Klucken J, Eskofier BM, Merola A, Horak F, Lang AE, Reilmann R, Giuffrida J, Nieuwboer A, Horne M, Little MA, Litvan I, Simuni T, Dorsey ER, Burack MA, Kubota K, Kamondi A, Godinho C, Daneault JF, Mitsi G, Krinke L, Hausdorff JM, Bloem BR, Papapetropoulos S, on behalf of the MDS Taskforce on Technology, “Technology in Parkinson Disease: Challenges and Opportunities”, Movement Disorders, 2016: 31(9): 1272-1282
  3. Tran D, Pajaro-Blazquez M, Daneault JF, Gallegos JG, Pons J, Fregni F, Bonato P, Zafonte R, “Combining Dopaminergic Facilitation with Robot-Assisted Upper-Limb Therapy in Stroke Survivors, A Position Paper”, Am J Phys Med Rehabil, 2016; 95(6): 459-474
  4. Schneider JC, Ozsecen MY, Muraoka NK, Mancinelli C, Della Croce U, Ryan CM, Bonato P, Feasibility of an Exoskeleton-Based Interactive Video Game System for Upper Extremity Burn Contractures, PM&R, 2016; 8(5): 445-452
  5. Jacobson E., Meleger A., Bonato P., Wayne P., Langevin H., Kaptchuk T.J., Davis R.B., “Structural Integration as an Adjunct to Outpatient Rehabilitation for Chronic Non-Specific Low Back Pain: a Randomized Pilot Clinical Trial”, Evidence-Based Complementary and Alternative Medicine, 2015, ID 813418, 19
  6. Dai C., Li Y., Christie A., Bonato P., McGill K.C., Clancy E.A., “Cross-Comparison of Three Electromyogram Decomposition Algorithms Assessed with Experimental and Simulated Data”, IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2015 Jan;23(1):32-40
  7. Coscia M., Cheung V.C.K., Tropea P., Koenig A., Monaco V., Bennis C., Micera S., Bonato P., “The Effect of Arm Weight Support on Upper Limb Muscle Synergies during Reaching Movements”, J Neuroeng Rehabil, 2014 Mar 4;11(1):22
  8. Della Croce U., Crapanzano F., Li L., Kasi P.K., Patritti B.L., Mancinelli C., Hunter D.J., Stamenović D., Harvey W.F., Bonato P., “Effects of a Novel Pneumatic Unloading Knee Brace on the Gait Mechanics of Patients with Knee Osteoarthritis”, PM&R 2013; 5(10): 816-824
  9. Pietrusinski M, Cajigas I, Bonato P. Mavroidis C., Robotic Gait Rehabilitation Trainer, IEEE/ASME Transactions on Mechatronics 2013; 99: 1-10
  10. Dalton A, Patel S, Chowdhury AR, Welsh M, Pang T, Schachter S, ÓLaighin G, Bonato P. Development of a Body Sensor Network to Detect Motor Patterns of Epileptic Seizures. IEEE Trans Biomed Eng, 2012; 59(11): 3204-3211
  11. Cheung VCK, Turolla A, Agostini M, Silvoni S, Bennis C, Kasi P, Paganoni S, Bonato P, Bizzi E. Muscle Synergy Patterns as Physiological Markers of Motor Cortical Damage, Proceedings of the National Academy of Science. 2012; 109(36): 14652-14656
  12. Reinkensmeyer D.J., Bonato P., Boninger M.L., Chan L., Cowan R.E., Fregly B.J., Rodgers MM, “Major Trends in Mobility Technology Research and Development: Overview the Results of the NSF-WTEC European Study”, J Neuroeng Rehabil, 2012; 9: 22
  13. Patel S., Park H., Bonato P., Chan L., Rodgers M., “A Review of Wearable Sensors and Systems with Application in Rehabilitation”, J Neuroeng Rehabil, 2012; 9: 21
  14. Wayne P.M., Kiel D.P., Buring J.E., Connors E.M., Bonato P., Yeh G.Y., Cohen C.J., Mancinelli C., Davis R.B., “Impact of Tai Chi Exercise on Multiple Fracture-Related Risk Factors in Post-Menopausal Osteopenic Women: A Pilot Pragmatic, Randomized Trial”, BMC Complement Altern Med. 2012 Jan 30;12(1):7
  15. Benedetti M.G., Agostini V., Knaflitz M., Bonato P., “Muscle Activation Patterns During Level Walking and Stair Ambulation”, in Applications of EMG in Clinical and Sports Medicine, C. Steele (editor), InTech http://www.intechopen.com/books/show/title/applications-of-emg-in-clinical-and-sports-medicine, 2012
  16. Mavroidis C, Ranky RG, Sivak ML, Patritti BL, DiPisa J, Caddle A, Gilhooly K, Govoni L, Sivak S, Lancia M, Drillio R, Bonato P., Patient Specific Ankle-Foot Orthoses Using Rapid Prototyping. J Neuroeng Rehabil, 2011; 8: 1
  17. Chen B.R., Patel S., Buckley T., Rednic R., McClure D.J., Shih L., Tarsy D., Welsh M., Bonato P., A Web-Based System for Home Monitoring of Patients with Parkinson’s Disease Using Wearable Sensors. IEEE Trans Biomed Eng 2011; 58(3): 831-836
  18. Burke DT, Protopapas M, Bonato P, Burke JT, Landrum RF, “Martial Arts: Time Needed for Training”,Asian J Sports Med. 2011 Mar; 2(1): 31-36